Fi Europe

Micro-encapsulation: Encapsulation from the liquid. Combination of drying, granulation and release control in one step. Protection of sensitive ingredients. Safe embedding of volatile substances. Microcapsules in solid matrix for perfect enclosure and protection of sensitive substances Valuable substances that require special protection are often present in powder or even liquid form. This encapsulation process is used in particular for products and ingredients for the food industry. These include probiotics or essential oils, fragrances and flavors, for example. Micro-encapsulation in the fluid bed or spouted bed allows these substances to be embedded in matrix pellets, thus combining drying, granule formation and release control in a single step. The substances to be protected are emulsified and then gently granulated on the basis of spray granulation and thereby embedded homogeneously distributed in a compact protective matrix. In the field of micro-encapsulation, Glatt has conducted various case studies on formulation and process optimization strategies based on encapsulation efficiency. Depending on the preferred principle, based on the properties of the…

Enhanced efficacy of coenzyme Q10, curcuma or similar ingredients To enable the body to absorb essential nutrients While this issue is the most essential for the formulation of pharmaceutical dosage forms, as it determines the efficacy of the drug, studies on the uptake of dietary supplements are only just beginning. However, water-insoluble substances cannot be absorbed by the body and must therefore be converted into a soluble micellar structure. In liquid form, these formulations have a limited shelflife stability, so a drying step follows, which produces a wide variety of product forms ranging from readily mixable powders to dust-free, easily soluble granules or compact, defined pellets. The moderate and precisely controllable process temperature in the fluidized bed or spouted bed is particularly suitable for sensitive active ingredients. Coenzyme Q10, curcuma or similar substances are typical candidates for improving bioavailability. The process steps required for this can be completely tested from micelle formation to…